Basic research
Direct SpoIIQ-SpoIIIAH interaction is dispensable for sporulation in Bacillus subtilis

Authors: I. Barák, K. Muchová, A. Vetráková, J. Júdová, Z. Chromiková




Projects:

VEGA 2/0016/25- Mechanizmus pohltenia prespóry materskou bunkou počas sporulácie Bacillus subtilis. 
APVV-22-0303- Molekulárny mechanizmus meracieho zariadenia na nájdenie správneho miesta bakteriálneho asymetrického bunkového delenia.
Plán obnovy a odolnosti SR - 09103-03-V06-00080- Molekulárny mechanizmus meracieho zariadenia na nájdenie správneho miesta bakteriálneho asymetrického bunkového delenia.

Publications:

UCHOVÁ, Katarína* - VETRÁKOVÁ, Andrea* - BRANNIGAN, J.A. - SIDHU, Sonam - JÚDOVÁ, Jana - CHROMÍKOVÁ, Zuzana - WILKINSON, A.J. - BARÁK, Imrich**. Direct SpoIIQ-SpoIIIAH interaction is dispensable for sporulation in Bacillus subtilis. In Journal of Biological Chemistry, 2025, vol. 301, iss. 12, art. no. 110934. (2024: 3.9 - IF, Q2 - JCR, 1.705 - SJR, Q1 - SJR). ISSN 0021-9258. Dostupné na: https://doi.org/10.1016/j.jbc.2025.110934

Basic research
Two phosphomimetic sites in the GABA transporter GAT1 C-terminus selectively regulate transporter interactions with distinct types of PDZ domains in vitro

Authors: I. Koščová, M. Baliová, F. Jurský




Projects:

EGA 2/0076/25- PDZ interakcia CADM1 s npro-interleukínom-16

Publications:

KOŠČOVÁ, Iveta - BALIOVÁ, Martina - JURSKÝ, František. Two phosphomimetic sites in the GABA transporter GAT1 C-terminus selectively regulate transporter interactions with distinct types of PDZ domains in vitro. In Neurochemistry International, 2025, vol. 190, art. no. 106058. (2024: 4 - IF, Q2 - JCR, 1.193 - SJR, Q2 - SJR). ISSN 0197-0186. Dostupné na: https://doi.org/10.1016/j.neuint.2025.106058

Basic research
The extreme C-terminal region of the phage BFK20 gp41 helicase has a role in DNA binding, protein-ATP interactions and ATPase activity

Authors: G. Bukovská, N. Halgašová, L. Bocánova, J. A. Bauer, B. Niku




Projects:

VEGA 2/0079/22 - Príprava mutantných lytických a replikačných proteínov bakteriofágov a ich antibakteriálny potenciál

Publications:

HALGAŠOVÁ, Nora - BOCÁNOVÁ, Lucia - BAUER, Jacob - NIKU, Barbora - PÁPAYOVÁ, Kristína - BUKOVSKÁ, Gabriela**. The extreme C-terminal region of the phage BFK20 gp41 helicase has a role in DNA binding, protein-ATP interactions and ATPase activity. In Biochimie, 2025, vol. 238, pp. 43-57. (2024: 3 - IF, Q3 - JCR, 0.884 - SJR, Q2 - SJR). ISSN 0300-9084. Dostupné na: https://doi.org/10.1016/j.biochi.2025.07.022

Applied research
Microbiome and response to cleaning and biocidal treatments on granite historical buildings using MinION sequencing

Authors: F. Maisto, J. Pavlović, L. Kraková, D. Pangallo




Projects:

VEGA 2/0086/25 - Vývoj postupov biočistenia na odstraňovanie syntetických polymérov z povrchov objektov kultúrneho dedičstva.

APVV-23-0235 - Biologické čistenie (biocleaning): mikroorganizmy a ich enzýmy pre efektívne odstraňovanie syntetických polymérov z povrchov objektov kultúrneho dedičstva.

Publications:

MAISTO, Francesca - MÉNDEZ, Anxo - PAVLOVIĆ, Jelena - KRAKOVÁ, Lucia - SANMARTÍN, Patricia - PANGALLO, Domenico. Microbiome and response to cleaning and biocidal treatments on granite historical buildings using MinION sequencing. In Construction and Building Materials, 2025, vol. 490, art. no. 142589. (2024: 8 - IF, Q1 - JCR, 2.094 - SJR, Q1 - SJR). ISSN 0950-0618. Dostupné na: https://doi.org/10.1016/j.conbuildmat.2025.142589

International research projects
Dividing the ?-amylase family GH57 of starch hydrolases and related enzymes into subfamilies using evolutionary, clustering and functional criteria

Authors: Š. Janeček, A. Poláček




Projects:

VEGA (2025-2028) – 2/0096/25: „Amylolytické enzýmy – in silico prístupy k štúdiu ich sekvencií, štruktúr, špecificít a evolúcie“

Publications:

POLÁČEK, Adam - LOMBARD, Vincent - COUTINHO, Pedro M. - TERRAPON, Nicolas - JANEČEK, Štefan**. Dividing the α-amylase family GH57 of starch hydrolases and related enzymes into subfamilies using evolutionary, clustering and functional criteria. In International Journal of Biological Macromolecules, 2025, vol. 309, part. 2, art. no. 142823. (2024: 8.5 - IF, Q1 - JCR, 1.285 - SJR, Q1 - SJR). ISSN 0141-8130. Dostupné na: https://doi.org/10.1016/j.ijbiomac.2025.142823

International research projects
G-quadruplex-driven molecular disassembly and type I-to-type II photophysical conversion of a heavy-atom-free photosensitizer for site-specific oxidative damage

Authors: J. Jamroskoškovič, MV. Cottini




Projects:

Impulz-IM-2022-62. G-quadruplex DNA for Genetic Engineering in Bacteria

Publications:

SACZUK, Katarzyna - COTTINI, Maria V. - DUDEK, Marta - MAZUR, Leszek M. - SÁNCHEZ, Dario Puchán - LÓPEZ-PACIOS, Lucía - KASSEM, Ahmad - MATCYSZYN, Katarzyna - NOGUEIRA, Juan J. - MONNEREAU, Cyrille - MARTÍNEZ-FERNÁNDEZ, Lara - JAMROŠKOVIČ, Ján - CABANETOS, Clément - DEIANA, Marco. G-quadruplex-driven molecular disassembly and type I-to-type II photophysical conversion of a heavy-atom-free photosensitizer for site-specific oxidative damage. In Nanoscale Horizons, 2025, vol. 10, iss. 8, pp. 1660-1673. (2024: 6.6 - IF, Q1 - JCR, 1.735 - SJR, Q1 - SJR). ISSN 2055-6756. Dostupné na: https://doi.org/10.1039/d5nh00237k